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Synthesis and Characterization of a New Peptide Prodrug of Glucosamine with Enhanced Gut Permeability
The aim of this study was to synthesize a peptide prodrug of glucosamine (GlcN) with increased gut permeability through the gut peptide transporter 1 (PepT1). Glycine-Valine ester derivative of GlcN (GVG) was synthesised using solid phase synthesis followed by characterization and evaluation of its...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433102/ https://www.ncbi.nlm.nih.gov/pubmed/25978315 http://dx.doi.org/10.1371/journal.pone.0126786 |