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Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine

BACKGROUND: Ossabaw miniature swine when fed a diet high in fructose, saturated fat and cholesterol (NASH diet) develop metabolic syndrome and nonalcoholic steatohepatitis (NASH) characterized by liver injury and fibrosis. This study was conducted to further characterize the development of NASH in t...

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Detalles Bibliográficos
Autores principales: Liang, Tiebing, Alloosh, Mouhamad, Bell, Lauren N., Fullenkamp, Allison, Saxena, Romil, Van Alstine, William, Bybee, Phelan, Werling, Klára, Sturek, Michael, Chalasani, Naga, Masuoka, Howard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433111/
https://www.ncbi.nlm.nih.gov/pubmed/25978364
http://dx.doi.org/10.1371/journal.pone.0124173