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Endoplasmic Reticulum Stress Impairs Insulin Receptor Signaling in the Brains of Obese Rats

The incidence of obesity is increasing worldwide. It was reported that endoplasmic reticulum stress (ERS) could inhibit insulin receptor signaling by activating c-Jun N-terminal kinase (JNK) in the liver. However, the relationship between ERS and insulin receptor signaling in the brain during obesit...

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Detalles Bibliográficos
Autores principales: Liang, Lina, Chen, Jing, Zhan, Libin, Lu, Xiaoguang, Sun, Xiaoxin, Sui, Hua, Zheng, Luping, Xiang, Hong, Zhang, Fuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433117/
https://www.ncbi.nlm.nih.gov/pubmed/25978724
http://dx.doi.org/10.1371/journal.pone.0126384