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Endoplasmic Reticulum Stress Impairs Insulin Receptor Signaling in the Brains of Obese Rats
The incidence of obesity is increasing worldwide. It was reported that endoplasmic reticulum stress (ERS) could inhibit insulin receptor signaling by activating c-Jun N-terminal kinase (JNK) in the liver. However, the relationship between ERS and insulin receptor signaling in the brain during obesit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433117/ https://www.ncbi.nlm.nih.gov/pubmed/25978724 http://dx.doi.org/10.1371/journal.pone.0126384 |