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Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma

Pleuropulmonary Blastoma (PPB) is the primary neoplastic manifestation of a pediatric cancer predisposition syndrome that is associated with several diseases including cystic nephroma, Wilms tumor, neuroblastoma, rhabdomyosarcoma, medulloblastoma, and ovarian Sertoli-Leydig cell tumor. The primary p...

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Detalles Bibliográficos
Autores principales: Yin, Yongjun, Castro, Angela M., Hoekstra, Marrit, Yan, Thomas J., Kanakamedala, Ajay C., Dehner, Louis P., Hill, D. Ashley, Ornitz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433140/
https://www.ncbi.nlm.nih.gov/pubmed/25978641
http://dx.doi.org/10.1371/journal.pgen.1005242