Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches

BACKGROUND: Fasciola hepatica is the causative agent of fascioliasis, a disease affecting grazing animals, causing economic losses in global agriculture and currently being an important human zoonosis. Overuse of chemotherapeutics against fascioliasis has increased the populations of drug resistant...

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Detalles Bibliográficos
Autores principales: Hernández Alvarez, Lilian, Naranjo Feliciano, Dany, Hernández González, Jorge Enrique, de Oliveira Soares, Rosemberg, Barreto Gomes, Diego Enry, Pascutti, Pedro Geraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433193/
https://www.ncbi.nlm.nih.gov/pubmed/25978322
http://dx.doi.org/10.1371/journal.pntd.0003759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433193/
https://www.ncbi.nlm.nih.gov/pubmed/25978322
http://dx.doi.org/10.1371/journal.pntd.0003759

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