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Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse

Genetic predisposition and environmental factors influence the development of human autoimmune disease. Occupational exposure to crystalline silica (cSiO(2)) has been etiologically linked to increased incidence of autoimmunity, including systemic lupus erythematosus (SLE), but the underlying mechani...

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Detalles Bibliográficos
Autores principales: Bates, Melissa A., Brandenberger, Christina, Langohr, Ingeborg, Kumagai, Kazuyoshi, Harkema, Jack R., Holian, Andrij, Pestka, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433215/
https://www.ncbi.nlm.nih.gov/pubmed/25978333
http://dx.doi.org/10.1371/journal.pone.0125481