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Immunoproteasome Deficiency Protects in the Retina after Optic Nerve Crush

The immunoproteasome is upregulated by disease, oxidative stress, and inflammatory cytokines, suggesting an expanded role for the immunoproteasome in stress signaling that goes beyond its canonical role in generating peptides for antigen presentation. The signaling pathways that are regulated by the...

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Detalles Bibliográficos
Autores principales: Schuld, Nathan J., Hussong, Stacy A., Kapphahn, Rebecca J., Lehmann, Ute, Roehrich, Heidi, Rageh, Abrar A., Heuss, Neal D., Bratten, Wendy, Gregerson, Dale S., Ferrington, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433222/
https://www.ncbi.nlm.nih.gov/pubmed/25978061
http://dx.doi.org/10.1371/journal.pone.0126768