Premature Expression of Foxp3 in Double-Negative Thymocytes

Peripheral immune regulation depends on the generation of thymic-derived regulatory T (tT(reg)) cells to maintain self-tolerance and to counterbalance overshooting immune responses. The expression of the T(reg) lineage defining transcription factor Foxp3 in developing tT(reg) cells depends on TCR si...

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Detalles Bibliográficos
Autores principales: Barra, Melanie M., Richards, David M., Hofer, Ann-Cathrin, Delacher, Michael, Feuerer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433242/
https://www.ncbi.nlm.nih.gov/pubmed/25978037
http://dx.doi.org/10.1371/journal.pone.0127038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433242/
https://www.ncbi.nlm.nih.gov/pubmed/25978037
http://dx.doi.org/10.1371/journal.pone.0127038

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