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A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway

A lipopolysaccharide from Pantoea agglomerans (LPSpa) has been applied to various fields for human use as a Toll-like receptor 4 ligand and its safety has been confirmed. Here, we showed for the first time the application of LPSpa as an effective mucosal adjuvant for activating vaccine-induced antig...

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Detalles Bibliográficos
Autores principales: Fukasaka, Masahiro, Asari, Daisuke, Kiyotoh, Eiji, Okazaki, Arimichi, Gomi, Yasuyuki, Tanimoto, Takeshi, Takeuchi, Osamu, Akira, Shizuo, Hori, Mitsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433252/
https://www.ncbi.nlm.nih.gov/pubmed/25978818
http://dx.doi.org/10.1371/journal.pone.0126849