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A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway
A lipopolysaccharide from Pantoea agglomerans (LPSpa) has been applied to various fields for human use as a Toll-like receptor 4 ligand and its safety has been confirmed. Here, we showed for the first time the application of LPSpa as an effective mucosal adjuvant for activating vaccine-induced antig...
Autores principales: | Fukasaka, Masahiro, Asari, Daisuke, Kiyotoh, Eiji, Okazaki, Arimichi, Gomi, Yasuyuki, Tanimoto, Takeshi, Takeuchi, Osamu, Akira, Shizuo, Hori, Mitsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433252/ https://www.ncbi.nlm.nih.gov/pubmed/25978818 http://dx.doi.org/10.1371/journal.pone.0126849 |
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