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Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis

Mycobacterial tuberculosis (Mtb) is able to preserve its intrabacterial pH (pH(IB)) near neutrality in the acidic phagosomes of immunologically activated macrophages and to cause lethal pathology in immunocompetent mice. In contrast, when its ability to maintain pH(IB) homeostasis is genetically com...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Sun, Mingna, Burns-Huang, Kristin, Jiang, Xiuju, Ling, Yan, Darby, Crystal, Ehrt, Sabine, Liu, Gang, Nathan, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433263/
https://www.ncbi.nlm.nih.gov/pubmed/25978362
http://dx.doi.org/10.1371/journal.pone.0126211