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Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis
Mycobacterial tuberculosis (Mtb) is able to preserve its intrabacterial pH (pH(IB)) near neutrality in the acidic phagosomes of immunologically activated macrophages and to cause lethal pathology in immunocompetent mice. In contrast, when its ability to maintain pH(IB) homeostasis is genetically com...
Autores principales: | Zhao, Nan, Sun, Mingna, Burns-Huang, Kristin, Jiang, Xiuju, Ling, Yan, Darby, Crystal, Ehrt, Sabine, Liu, Gang, Nathan, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433263/ https://www.ncbi.nlm.nih.gov/pubmed/25978362 http://dx.doi.org/10.1371/journal.pone.0126211 |
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