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Computational Identification of Antigenicity-Associated Sites in the Hemagglutinin Protein of A/H1N1 Seasonal Influenza Virus

The antigenic variability of influenza viruses has always made influenza vaccine development challenging. The punctuated nature of antigenic drift of influenza virus suggests that a relatively small number of genetic changes or combinations of genetic changes may drive changes in antigenic phenotype...

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Detalles Bibliográficos
Autores principales: Ren, Xiaowei, Li, Yuefeng, Liu, Xiaoning, Shen, Xiping, Gao, Wenlong, Li, Juansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433265/
https://www.ncbi.nlm.nih.gov/pubmed/25978416
http://dx.doi.org/10.1371/journal.pone.0126742