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Computational Identification of Antigenicity-Associated Sites in the Hemagglutinin Protein of A/H1N1 Seasonal Influenza Virus
The antigenic variability of influenza viruses has always made influenza vaccine development challenging. The punctuated nature of antigenic drift of influenza virus suggests that a relatively small number of genetic changes or combinations of genetic changes may drive changes in antigenic phenotype...
Autores principales: | Ren, Xiaowei, Li, Yuefeng, Liu, Xiaoning, Shen, Xiping, Gao, Wenlong, Li, Juansheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433265/ https://www.ncbi.nlm.nih.gov/pubmed/25978416 http://dx.doi.org/10.1371/journal.pone.0126742 |
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