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Antitumor Effects of Oncolytic Adenovirus-Carrying siRNA Targeting Potential Oncogene EphA3

Conditionally replicating adenoviruses (CRAds) armed with antitumor transgenes hold promise for cancer treatment. In previous studies, we showed that the 1504-siRNA targeting potential oncogene EphA3 was an efficient therapeutic transgene and that the telomerase reverse transcriptase promoter (TERTp...

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Detalles Bibliográficos
Autores principales: Zhao, Yali, Li, Hailiang, Wu, Ruiqin, Li, Shanhu, Wang, Peng, Wang, Hongtao, Wang, Jian, Zhou, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433270/
https://www.ncbi.nlm.nih.gov/pubmed/25978371
http://dx.doi.org/10.1371/journal.pone.0126726