Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major

Leishmania spp. is a protozoan parasite and the causative agent of leishmaniasis. Thymidine kinase (TK) catalyses the transfer of the γ-phosphate of ATP to 2’-deoxythymidine (dThd) forming thymidine monophosphate (dTMP). L. major Type II TK (LmTK) has been previously shown to be important for infect...

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Detalles Bibliográficos
Autores principales: Timm, Jennifer, Bosch-Navarrete, Cristina, Recio, Eliseo, Nettleship, Joanne E., Rada, Heather, González-Pacanowska, Dolores, Wilson, Keith S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433323/
https://www.ncbi.nlm.nih.gov/pubmed/25978379
http://dx.doi.org/10.1371/journal.pntd.0003781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433323/
https://www.ncbi.nlm.nih.gov/pubmed/25978379
http://dx.doi.org/10.1371/journal.pntd.0003781

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