The Influence of Genetic Variability and Proinflammatory Status on the Development of Bone Disease in Patients with Gaucher Disease

Gaucher disease, the most common lysosomal storage disorder, is caused by β-glucocerebrosidase deficiency. Bone complications are the major cause of morbidity in patients with type 1 Gaucher disease (GD1). Genetic components strongly influence bone remodelling. In addition, chronic inflammation prod...

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Detalles Bibliográficos
Autores principales: Gervas-Arruga, Javier, Cebolla, Jorge Javier, de Blas, Ignacio, Roca, Mercedes, Pocovi, Miguel, Giraldo, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433334/
https://www.ncbi.nlm.nih.gov/pubmed/25978039
http://dx.doi.org/10.1371/journal.pone.0126153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433334/
https://www.ncbi.nlm.nih.gov/pubmed/25978039
http://dx.doi.org/10.1371/journal.pone.0126153

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