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Biochemical and Functional Comparisons of mdx and Sgcg (−/−) Muscular Dystrophy Mouse Models

Mouse models have provided an essential platform to investigate facets of human diseases, from etiology, diagnosis, and prognosis, to potential treatments. Muscular dystrophy (MD) is the most common human genetic disease occurring in approximately 1 in 2500 births. The mdx mouse, which is dystrophin...

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Detalles Bibliográficos
Autores principales: Roberts, Nathan W., Holley-Cuthrell, Jenan, Gonzalez-Vega, Magdalis, Mull, Aaron J., Heydemann, Ahlke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433636/
https://www.ncbi.nlm.nih.gov/pubmed/26064876
http://dx.doi.org/10.1155/2015/131436