Cargando…
CD40 Ligand Deficient C57BL/6 Mouse Is a Potential Surrogate Model of Human X-Linked Hyper IgM (X-HIGM) Syndrome for Characterizing Immune Responses against Pathogens
Individuals with X-HIGM syndrome fail to express functional CD40 ligand; consequently they cannot mount effective protective antibody responses against pathogenic bacteria. We evaluated, compared, and characterized the humoral immune response of wild type (WT) and C57-CD40L deficient (C57-CD40L(−/−)...
Autores principales: | Lopez-Saucedo, Catalina, Bernal-Reynaga, Rodolfo, Zayas-Jahuey, Jesus, Galindo-Gomez, Silvia, Shibayama, Mineko, Garcia-Galvez, Carlos, Estrada-Parra, Sergio, Estrada-Garcia, Teresa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433659/ https://www.ncbi.nlm.nih.gov/pubmed/26064940 http://dx.doi.org/10.1155/2015/679850 |
Ejemplares similares
-
X-linked Hyper IgM (HIGM1) in an African kindred: the first report from South Africa
por: Pienaar, Sandra, et al.
Publicado: (2003) -
Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects
por: Jhamnani, Rekha D., et al.
Publicado: (2018) -
X-linked Hyper-IgM Syndrome with Bronchiectasis
por: Nandan, Devki, et al.
Publicado: (2014) -
Elevated levels of enteric IgA in an unimmunised mouse model of Hyper IgM syndrome derived from gut-associated secondary lymph organs even in the absence of germinal centres
por: Hernandez-Cazares, Felipe, et al.
Publicado: (2023) -
Progressive choreodystonia in X‐linked hyper‐IgM immunodeficiency: a rare but recurrent presentation
por: Škorvánek, Matej, et al.
Publicado: (2022)