CD40 Ligand Deficient C57BL/6 Mouse Is a Potential Surrogate Model of Human X-Linked Hyper IgM (X-HIGM) Syndrome for Characterizing Immune Responses against Pathogens

Individuals with X-HIGM syndrome fail to express functional CD40 ligand; consequently they cannot mount effective protective antibody responses against pathogenic bacteria. We evaluated, compared, and characterized the humoral immune response of wild type (WT) and C57-CD40L deficient (C57-CD40L(−/−)...

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Detalles Bibliográficos
Autores principales: Lopez-Saucedo, Catalina, Bernal-Reynaga, Rodolfo, Zayas-Jahuey, Jesus, Galindo-Gomez, Silvia, Shibayama, Mineko, Garcia-Galvez, Carlos, Estrada-Parra, Sergio, Estrada-Garcia, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433659/
https://www.ncbi.nlm.nih.gov/pubmed/26064940
http://dx.doi.org/10.1155/2015/679850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433659/
https://www.ncbi.nlm.nih.gov/pubmed/26064940
http://dx.doi.org/10.1155/2015/679850

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