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Characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster from Penicillium coprobium

Pyripyropenes potently and selectively inhibit acyl-CoA:cholesterol acyltransferase 2 (ACAT-2). Among multiple isomers of pyripyropene (A to R), pyripyropene A (PyA) has insecticidal properties in addition to its growth inhibition properties against human umbilical vein endothelial cells. Based on t...

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Detalles Bibliográficos
Autores principales: Hu, Jie, Furutani, Ayako, Yamamoto, Kentaro, Oyama, Kazuhiko, Mitomi, Masaaki, Anzai, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434069/
https://www.ncbi.nlm.nih.gov/pubmed/26019565
http://dx.doi.org/10.1080/13102818.2014.960140