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Characterization of two acetyltransferase genes in the pyripyropene biosynthetic gene cluster from Penicillium coprobium
Pyripyropenes potently and selectively inhibit acyl-CoA:cholesterol acyltransferase 2 (ACAT-2). Among multiple isomers of pyripyropene (A to R), pyripyropene A (PyA) has insecticidal properties in addition to its growth inhibition properties against human umbilical vein endothelial cells. Based on t...
Autores principales: | Hu, Jie, Furutani, Ayako, Yamamoto, Kentaro, Oyama, Kazuhiko, Mitomi, Masaaki, Anzai, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434069/ https://www.ncbi.nlm.nih.gov/pubmed/26019565 http://dx.doi.org/10.1080/13102818.2014.960140 |
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