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Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds

Caspase-3 has been identified as a key mediator of neuronal apoptosis. The present study identifies caspase-3 as a common player involved in the regulation of multineurodegenerative disorders, namely, Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and a...

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Detalles Bibliográficos
Autores principales: Khan, Saif, Ahmad, Khurshid, Alshammari, Eyad M. A., Adnan, Mohd, Baig, Mohd Hassan, Lohani, Mohtashim, Somvanshi, Pallavi, Haque, Shafiul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434175/
https://www.ncbi.nlm.nih.gov/pubmed/26064904
http://dx.doi.org/10.1155/2015/379817