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Pim-2/mTORC1 Pathway Shapes Inflammatory Capacity in Rheumatoid Arthritis Synovial Cells Exposed to Lipid Peroxidations

Rheumatoid arthritis is a systemic autoimmune disease characterized by chronic inflammation of multiple joints, with disruption of joint cartilage. The proliferation of synovial fibroblasts in response to multiple inflammation factors is central to the pathogenesis of rheumatoid arthritis. Our previ...

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Detalles Bibliográficos
Autores principales: Yin, Geng, Li, Yan, Yang, Min, Cen, Xiao-min, Xie, Qi-bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434176/
https://www.ncbi.nlm.nih.gov/pubmed/26064888
http://dx.doi.org/10.1155/2015/240210