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Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial

BACKGROUND: Despite the high prevalence and global impact of knee osteoarthritis (KOA), current treatments are palliative. No disease modifying anti-osteoarthritic drug (DMOAD) has been approved. We recently demonstrated significant involvement of uric acid and activation of the innate immune respon...

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Detalles Bibliográficos
Autores principales: Leung, Ying-Ying, Thumboo, Julian, Wong, Bak Siew, Haaland, Ben, Chowbay, Balram, Chakraborty, Bibhas, Tan, Mann Hong, Kraus, Virginia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434529/
https://www.ncbi.nlm.nih.gov/pubmed/25925674
http://dx.doi.org/10.1186/s13063-015-0726-x