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Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial
BACKGROUND: Despite the high prevalence and global impact of knee osteoarthritis (KOA), current treatments are palliative. No disease modifying anti-osteoarthritic drug (DMOAD) has been approved. We recently demonstrated significant involvement of uric acid and activation of the innate immune respon...
Autores principales: | Leung, Ying-Ying, Thumboo, Julian, Wong, Bak Siew, Haaland, Ben, Chowbay, Balram, Chakraborty, Bibhas, Tan, Mann Hong, Kraus, Virginia B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434529/ https://www.ncbi.nlm.nih.gov/pubmed/25925674 http://dx.doi.org/10.1186/s13063-015-0726-x |
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