Cargando…

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture

The conserved MICOS complex functions as a primary determinant of mitochondrial inner membrane structure. We address the organization and functional roles of MICOS and identify two independent MICOS subcomplexes: Mic27/Mic10/Mic12, whose assembly is dependent on respiratory complexes and the mitocho...

Descripción completa

Detalles Bibliográficos
Autores principales: Friedman, Jonathan R, Mourier, Arnaud, Yamada, Justin, McCaffery, J Michael, Nunnari, Jodi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434539/
https://www.ncbi.nlm.nih.gov/pubmed/25918844
http://dx.doi.org/10.7554/eLife.07739