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Multiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasite

During its asexual development within the red blood cell (RBC), Plasmodium falciparum (Pf), the most virulent human malaria parasite, exports proteins that modify the host RBC membrane. The attendant increase in cell stiffness and cytoadherence leads to sequestration of infected RBCs in microvascula...

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Detalles Bibliográficos
Autores principales: Zhang, Yao, Huang, Changjin, Kim, Sangtae, Golkaram, Mahdi, Dixon, Matthew W. A., Tilley, Leann, Li, Ju, Zhang, Sulin, Suresh, Subra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434686/
https://www.ncbi.nlm.nih.gov/pubmed/25918423
http://dx.doi.org/10.1073/pnas.1505584112