Cargando…
Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast
Antitumor substances related to vinblastine and vincristine are exclusively found in the Catharanthus roseus (Madagascar periwinkle), a member of the Apocynaceae plant family, and continue to be extensively used in cancer chemotherapy. Although in high demand, these valuable compounds only accumulat...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434687/ https://www.ncbi.nlm.nih.gov/pubmed/25918424 http://dx.doi.org/10.1073/pnas.1501821112 |