CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation

Mitosis is commonly thought to be associated with reduced cap-dependent protein translation. Here we show an alternative control mechanism for maintaining cap-dependent translation during mitosis revealed by a viral oncoprotein, Merkel cell polyomavirus small T (MCV sT). We find MCV sT to be a promi...

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Detalles Bibliográficos
Autores principales: Shuda, Masahiro, Velásquez, Celestino, Cheng, Erdong, Cordek, Daniel G., Kwun, Hyun Jin, Chang, Yuan, Moore, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434708/
https://www.ncbi.nlm.nih.gov/pubmed/25883264
http://dx.doi.org/10.1073/pnas.1505787112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434708/
https://www.ncbi.nlm.nih.gov/pubmed/25883264
http://dx.doi.org/10.1073/pnas.1505787112

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