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CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation
Mitosis is commonly thought to be associated with reduced cap-dependent protein translation. Here we show an alternative control mechanism for maintaining cap-dependent translation during mitosis revealed by a viral oncoprotein, Merkel cell polyomavirus small T (MCV sT). We find MCV sT to be a promi...
Autores principales: | Shuda, Masahiro, Velásquez, Celestino, Cheng, Erdong, Cordek, Daniel G., Kwun, Hyun Jin, Chang, Yuan, Moore, Patrick S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434708/ https://www.ncbi.nlm.nih.gov/pubmed/25883264 http://dx.doi.org/10.1073/pnas.1505787112 |
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