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A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL

Varicella-zoster virus (VZV), of the family Alphaherpesvirinae, causes varicella in children and young adults, potentially leading to herpes zoster later in life on reactivation from latency. The conserved herpesvirus glycoprotein gB and the heterodimer gHgL mediate virion envelope fusion with cell...

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Detalles Bibliográficos
Autores principales: Xing, Yi, Oliver, Stefan L., Nguyen, TuongVi, Ciferri, Claudio, Nandi, Avishek, Hickman, Julie, Giovani, Cinzia, Yang, Edward, Palladino, Giuseppe, Grose, Charles, Uematsu, Yasushi, Lilja, Anders E., Arvin, Ann M., Carfí, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434712/
https://www.ncbi.nlm.nih.gov/pubmed/25918416
http://dx.doi.org/10.1073/pnas.1501176112