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How a well-adapted immune system is organized

The repertoire of lymphocyte receptors in the adaptive immune system protects organisms from diverse pathogens. A well-adapted repertoire should be tuned to the pathogenic environment to reduce the cost of infections. We develop a general framework for predicting the optimal repertoire that minimize...

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Detalles Bibliográficos
Autores principales: Mayer, Andreas, Balasubramanian, Vijay, Mora, Thierry, Walczak, Aleksandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434741/
https://www.ncbi.nlm.nih.gov/pubmed/25918407
http://dx.doi.org/10.1073/pnas.1421827112