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Cas9-mediated targeting of viral RNA in eukaryotic cells

Clustered, regularly interspaced, short palindromic repeats–CRISPR associated (CRISPR-Cas) systems are prokaryotic RNA-directed endonuclease machineries that act as an adaptive immune system against foreign genetic elements. Using small CRISPR RNAs that provide specificity, Cas proteins recognize an...

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Detalles Bibliográficos
Autores principales: Price, Aryn A., Sampson, Timothy R., Ratner, Hannah K., Grakoui, Arash, Weiss, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434742/
https://www.ncbi.nlm.nih.gov/pubmed/25918406
http://dx.doi.org/10.1073/pnas.1422340112