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Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos

Fetal spleen is a major hematopoietic site prior to initiation of bone marrow hematopoiesis. Morphologic analysis suggested erythropoietic activity in fetal spleen, but it remained unclear how erythropoiesis was regulated. To address this question, we performed flow cytometric analysis and observed...

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Detalles Bibliográficos
Autores principales: Tan, Keai Sinn, Inoue, Tomoko, Kulkeaw, Kasem, Tanaka, Yuka, Lai, Mei I, Sugiyama, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434811/
https://www.ncbi.nlm.nih.gov/pubmed/25887124
http://dx.doi.org/10.1242/bio.201410686