Dock10, a Cdc42 and Rac1 GEF, induces loss of elongation, filopodia, and ruffles in cervical cancer epithelial HeLa cells

Dock10 is one of the three members of the Dock-D family of Dock proteins, a class of guanine nucleotide exchange factors (GEFs) for Rho GTPases. Its homologs Dock9 and Dock11 are Cdc42 GEFs. Dock10 is required for maintenance of rounded morphology and amoeboid-type movement. Full-length isoforms of...

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Detalles Bibliográficos
Autores principales: Ruiz-Lafuente, Natalia, Alcaraz-García, María-José, García-Serna, Azahara-María, Sebastián-Ruiz, Silvia, Moya-Quiles, María-Rosa, García-Alonso, Ana-María, Parrado, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434814/
https://www.ncbi.nlm.nih.gov/pubmed/25862245
http://dx.doi.org/10.1242/bio.20149050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434814/
https://www.ncbi.nlm.nih.gov/pubmed/25862245
http://dx.doi.org/10.1242/bio.20149050

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