Cargando…

A chicken model of pharmacologically-induced Hirschsprung disease reveals an unexpected role of glucocorticoids in enteric aganglionosis

The enteric nervous system originates from neural crest cells that migrate in chains as they colonize the embryonic gut, eventually forming the myenteric and submucosal plexus. Failure of the neural crest cells to colonize the gut leads to aganglionosis in the terminal gut, a pathological condition...

Descripción completa

Detalles Bibliográficos
Autores principales: Gasc, Jean-Marie, Clemessy, Maud, Corvol, Pierre, Kempf, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434818/
https://www.ncbi.nlm.nih.gov/pubmed/25836673
http://dx.doi.org/10.1242/bio.201410454