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Sphingosine-1-Phosphate and Its Effect on Glucose Deprivation/Glucose Reload Stress: From Gene Expression to Neuronal Survival

Sphingosine kinase-1 (Sphk1-1, EC 2.7.1.91) is a regulator of pro-survival signalling, and its alterations have been observed in Alzheimer’s disease, brain ischemia and other neurological disorders. In this study we addressed the question whether Sphk1 and its product, sphingosine-1-phosphate (S1P),...

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Detalles Bibliográficos
Autores principales: Czubowicz, Kinga, Cieślik, Magdalena, Pyszko, Joanna, Strosznajder, Joanna B., Strosznajder, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434862/
https://www.ncbi.nlm.nih.gov/pubmed/25056275
http://dx.doi.org/10.1007/s12035-014-8807-5