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Transthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the Hippocampus

Transthyretin (TTR) is the carrier protein of thyroxine (T(4)) and binds to retinol-binding protein (RBP)-retinol complex. It is mainly synthesized by both liver and choroid plexuses of the brain. Besides these properties, it has a neuroprotective role in several contexts such as Alzheimer’s disease...

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Detalles Bibliográficos
Autores principales: Vieira, Marta, Gomes, João R., Saraiva, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434863/
https://www.ncbi.nlm.nih.gov/pubmed/25084758
http://dx.doi.org/10.1007/s12035-014-8824-4