Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia

BACKGROUND: Preclinical testing of potential therapies for Duchenne muscular dystrophy (DMD) is conducted predominantly of the mdx mouse. But lack of a detailed quantitative description of the pathology of this animal limits our ability to evaluate the effectiveness of putative therapies or their re...

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Detalles Bibliográficos
Autores principales: Duddy, William, Duguez, Stephanie, Johnston, Helen, Cohen, Tatiana V, Phadke, Aditi, Gordish-Dressman, Heather, Nagaraju, Kanneboyina, Gnocchi, Viola, Low, SiewHui, Partridge, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434871/
https://www.ncbi.nlm.nih.gov/pubmed/25987977
http://dx.doi.org/10.1186/s13395-015-0041-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434871/
https://www.ncbi.nlm.nih.gov/pubmed/25987977
http://dx.doi.org/10.1186/s13395-015-0041-y

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