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Mitogen- and stress-activated Kinase 1 mediates Epstein-Barr virus latent membrane protein 1-promoted cell transformation in nasopharyngeal carcinoma through its induction of Fra-1 and c-Jun genes

BACKGROUND: Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase that serves as active link between extracellular signals and the primary response of gene expression. However, the involvement of MSK1 in malignant transformation and cancer development is not well understood. In this stud...

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Detalles Bibliográficos
Autores principales: Li, Binbin, Wan, Zheng, Huang, Guoliang, Huang, Zunnan, Zhang, Xiangning, Liao, Dan, Luo, Shengqun, He, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434874/
https://www.ncbi.nlm.nih.gov/pubmed/25958199
http://dx.doi.org/10.1186/s12885-015-1398-3