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Mitogen- and stress-activated Kinase 1 mediates Epstein-Barr virus latent membrane protein 1-promoted cell transformation in nasopharyngeal carcinoma through its induction of Fra-1 and c-Jun genes
BACKGROUND: Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase that serves as active link between extracellular signals and the primary response of gene expression. However, the involvement of MSK1 in malignant transformation and cancer development is not well understood. In this stud...
Autores principales: | Li, Binbin, Wan, Zheng, Huang, Guoliang, Huang, Zunnan, Zhang, Xiangning, Liao, Dan, Luo, Shengqun, He, Zhiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434874/ https://www.ncbi.nlm.nih.gov/pubmed/25958199 http://dx.doi.org/10.1186/s12885-015-1398-3 |
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