Single cell resolution in vivo imaging of DNA damage following PARP inhibition

Targeting DNA repair pathways is a powerful strategy to treat cancers. To gauge efficacy in vivo, typical response markers include late stage effects such as tumor shrinkage, progression free survival, or invasive repeat biopsies. These approaches are often difficult to answer critical questions suc...

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Detalles Bibliográficos
Autores principales: Yang, Katherine S., Kohler, Rainer H., Landon, Matthieu, Giedt, Randy, Weissleder, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434991/
https://www.ncbi.nlm.nih.gov/pubmed/25984718
http://dx.doi.org/10.1038/srep10129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434991/
https://www.ncbi.nlm.nih.gov/pubmed/25984718
http://dx.doi.org/10.1038/srep10129

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