Influence of cancer cachexia on drug liver metabolism and renal elimination in rats

BACKGROUND: Body wasting and cachexia change body composition and organ function, with effects on drug pharmacokinetics. The aim of this study was to investigate how cancer and cancer cachexia modify liver metabolism and renal drug elimination in rats. METHODS: Nine male Wistar-Han rats received a s...

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Detalles Bibliográficos
Autores principales: Cvan Trobec, Katja, Kerec Kos, Mojca, Trontelj, Jurij, Grabnar, Iztok, Tschirner, Anika, Palus, Sandra, Anker, Stefan D, Springer, Jochen, Lainscak, Mitja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435096/
https://www.ncbi.nlm.nih.gov/pubmed/26136411
http://dx.doi.org/10.1002/jcsm.12012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435096/
https://www.ncbi.nlm.nih.gov/pubmed/26136411
http://dx.doi.org/10.1002/jcsm.12012

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