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Nanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect

PURPOSE: The normal metabolite methylglyoxal (MG) specifically kills cancer cells by inhibiting glycolysis and mitochondrial respiration without much adverse effect upon normal cells. Though the anticancer property of MG is well documented, its gradual enzymatic degradation in vivo has prompted inte...

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Detalles Bibliográficos
Autores principales: Pal, Aparajita, Talukdar, Dipa, Roy, Anirban, Ray, Subhankar, Mallick, Asish, Mandal, Chitra, Ray, Manju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435252/
https://www.ncbi.nlm.nih.gov/pubmed/25999714
http://dx.doi.org/10.2147/IJN.S78284