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Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy

The development of robust nonviral vectors could facilitate clinical gene therapy applications and may overcome some of the immune complications of viral vectors. Nevertheless, most nonviral gene deliver approaches typically yield only transient and/or low gene expression. To address these caveats,...

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Detalles Bibliográficos
Autores principales: Di Matteo, Mario, Samara-Kuko, Emira, Ward, Natalie J, Waddingon, Simon N, McVey, John H, Chuah, Marinee KL, VandenDriessche, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435487/
https://www.ncbi.nlm.nih.gov/pubmed/25034357
http://dx.doi.org/10.1038/mt.2014.131