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Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

Accurate spatiotemporal assessment of extracellular vesicle (EV) delivery and cargo RNA translation requires specific and robust live-cell imaging technologies. Here we engineer optical reporters to label multiple EV populations for visualization and tracking of tumour EV release, uptake and exchang...

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Detalles Bibliográficos
Autores principales: Lai, Charles P., Kim, Edward Y., Badr, Christian E., Weissleder, Ralph, Mempel, Thorsten R., Tannous, Bakhos A., Breakefield, Xandra O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435621/
https://www.ncbi.nlm.nih.gov/pubmed/25967391
http://dx.doi.org/10.1038/ncomms8029