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The role of TGFBI (βig-H3) in gastrointestinal tract tumorigenesis

BACKGROUND: TGFβ-induced (TGFBI/βig-H3) is a protein inducible by TGFβ1 and secreted by many types of cells. It binds to collagen, forms part of the extracellular matrix (ECM), and interacts with integrins on cell surfaces. In this study, we investigated the role of TGFBI in tumorigenesis and the un...

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Detalles Bibliográficos
Autores principales: Han, Bing, Cai, Haolei, Chen, Ying, Hu, Bing, Luo, Hongyu, Wu, Yulian, Wu, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435624/
https://www.ncbi.nlm.nih.gov/pubmed/25889002
http://dx.doi.org/10.1186/s12943-015-0335-z