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Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis

Deregulated expression of heat shock proteins (HSPs) encoding genes is frequent in multiple myeloma. HSPs, which are molecular chaperones involved in protein homeostasis pathways, have emerged recently as promising therapeutic targets. Using human myeloma cell lines and primary myeloma cells belongi...

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Detalles Bibliográficos
Autores principales: Bustany, Sophie, Cahu, Julie, Descamps, Géraldine, Pellat-Deceunynck, Catherine, Sola, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435646/
https://www.ncbi.nlm.nih.gov/pubmed/25898974
http://dx.doi.org/10.1186/s13045-015-0135-3