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The Role of SUMO-Conjugating Enzyme Ubc9 in the Neuroprotection of Isoflurane Preconditioning Against Ischemic Neuronal Injury

Preconditioning with volatile anesthetics can create an ischemia tolerance against cerebral ischemia-reperfusion injury. We investigated whether ubiquitin conjugase 9 (Ubc9), the E2 conjugase for SUMOylation, is associated with neuroprotection induced by isoflurane preconditioning (IsoPC). In vitro,...

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Detalles Bibliográficos
Autores principales: Tong, Li, Wu, Zhixin, Ran, Mingzi, Chen, Yu, Yang, Lujia, Zhang, Haopeng, Zhang, Lina, Dong, Hailong, Xiong, Lize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435903/
https://www.ncbi.nlm.nih.gov/pubmed/24961570
http://dx.doi.org/10.1007/s12035-014-8797-3